The adjustment was made due to the new citation of EN ISO standard 21976:2020 "Packaging - Tamper verification features for medicinal product packaging" as a reference for consideration by manufacturers. The ISO standard has international validity. Previously, the document named the CEN standard EN 16679:2014 "Tamper Verification Features for medicinal product packaging" with Europe-wide relevance.

Source:

EC: Q&A on Safety features